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ea0065p285 | Neuroendocrinology | SFEBES2019

The argument for growth hormone day curve testing in acromegaly; significant discrepancy between mean growth hormone and random growth hormone levels

Healy Ultan , Kahn Shoaib , Vincent Alex , Martinez Jacinto , May Christine J H , Wass John , Shine Brian , Jafar-Mohammadi Bahram , Pal Aparna

Endocrine Society guidelines recommend random growth hormone (RGH) <1 mcg/l as indicative of biochemical control of acromegaly. Growth hormone (GH) control may also be determined using the mean GH (MGH) of a growth hormone day curve (GHDC). We report a retrospective analysis of 461 consecutive GHDCs, from 121 patients with treated acromegaly, performed in a single centre between 2009 and 2019. Each GHDC contained 79 GH measurements (mean 8.9) taken at regular interva...

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The argument for growth hormone day curve testing in acromegaly; significant discrepancy between mean growth hormone and random growth hormone levels

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